0
About
pxlence is a Ghent University spin-off company
founded in 2015 by Dr. Steve Lefever, Dr. Frauke Coppieters and Prof. Jo Vandesompele with an exclusive
commercial license for PCR assay design technology from Ghent University. Using the state-of-the-art
high-throughput primer design pipeline primerXL, almost one million
assays for amplification of DNA from both fresh frozen and formalin fixed parafin embedded (FFPE)
material covering over 99% of the human exome were expertly designed.
These best-in-class assays enable the enrichment of any exonic region of
interest for targeted resequencing or for confirmation of variants
by means of Sanger or next-generation sequencing. Approximately 6750 individual assays for 514 genes have
been tested in a diagnostic setting (ISO 15189) with a
wet-lab success rate exceeding 95%. Using our single-tube multiplex PCR
and library preparation technology, a 50-SNP Human Sample ID panel was released in
2020. Our customers include clinical diagnostic labs,
genetic centers, hospitals, and diagnostic or medical device companies in the field of PCR based
target enrichment.
Our company name pxlence (pronounced 'pixellence') refers to
primerXL : the in house developed primer design pipeline used to
create our assays
pixels : we see the image of the genome as our playground, we are
able to target any pixel you wish, either using our ready-to-go assays for the human exome or by designing
custom assays for any region of interest
excellence : we strive for excellent assay performance using universal PCR conditions
Management